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KMID : 0360220130540040645
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Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 4 p.645 ~ p.650
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A Case of Lymphomatoid Papulosis of the Eyelid
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Choi Youn-Joo
Jin Hyun-Chul
Khwarg Sang-In
Kim Nam-Ju
Choung Ho-Kyung
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Abstract
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Purpose: Lymphomatoid papulosis (LyP) is one of the primary cutaneous CD30-positive lymphoproliferative disorders. LyP of the eyelid has rarely been reported. Herein, a case of typical LyP of the medial canthal area is reported. In addition, a literature review was performed.
Case summary: A 40-year-old female presented with a skin mass in the medial canthal area of the left eye that developed 2 months earlier. Initially, a focal skin lesion developed, and even with conservative treatment at a local clinic, progressed to a mass lesion having a central ulceration and adjacent edema. After 6 weeks, the adjacent edema had gradually decreased. On ophthalmic examination, the left medial canthal lesion was a 6 x 6 mm sized elevated mass with a central crater covered by crust. The clinical impression was keratoacanthoma. The lesion was widely excised and reconstructed by a full-thickness skin graft after an incisional biopsy. Histopathologic findings showed dermal infiltration of various inflammatory cells with atypical lymphocytes showing positivity to the CD30 antigen, and LyP was diagnosed. Systemic evaluation showed no evidence of systemic lymphoma and the patient has remained free of recurrence or systemic disease after a 1-year follow-up.
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KEYWORD
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CD30 lymphoproliferative disease, Eyelid, Lymphomatoid papulosis
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